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Supplement evidence

165 / 575Research index — evidence review pending

Alpha-Lactalbumin

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The short answer

No use has passed JIVANA's study-level evidence review yet.

Evidence and scope
Research gathered — evidence review pending

This status does not grade the ingredient for every goal, outcome, or person.

Important limitation
No efficacy conclusion has passed JIVANA's study-level review yet. The linked research index is for discovery, not a benefit claim.
Before deciding
Identity, dose, interactions, product quality, and regulatory status still require review. Do not use this provisional page to decide whether to take it.

02 / EVIDENCE

What the research says

We keep supportive, mixed, negative, safety, and contextual findings together. The headline never replaces the underlying papers.

Study-level extraction is not complete yet.

This research-index page is live so the topic, source trail, and evidence boundaries are visible. Individual studies have not yet passed the JIVANA extraction and review process, so we do not manufacture an efficacy conclusion or research count from broad search results.

Unscreened discovery appendix—not evidence90 candidate publicationsSearch run: Aug 21, 2026

Complete for the displayed PubMed query at the search timestamp—not for all databases or every possible synonym. Candidates can be irrelevant, duplicate the same study, or report negative findings. They are never summed as evidence or participants until screened.

03 / SOURCES

Start with the source material

The live search is for discovery only. Search-result counts change and are not included in the audited totals above.

Recent PubMed discovery recordsDirect links to the first 12 records returned by the reproducible search. These are discovery candidates—not reviewed summaries or a count of supportive findings.
  1. A Systematic Review to Reassess the Formula for Early Life Growth.Nilaweera KN, van Sinderen D, Cotter PD · 2026 · Advances in nutrition (Bethesda, Md.) · PMID 42176955Open on PubMed
  2. Randomized Trial of Milk Oral Immunotherapy: Fixed Low-Dose vs Escalation to Medium-Dose.Nagakura KI, Takahashi K, Miura Y et al. · 2026 · The journal of allergy and clinical immunology. In practice · PMID 41633410Open on PubMed
  3. New infant formulas for healthy term infants: A randomized, controlled, double-blind, multicenter, non-inferiority design safety study.Fleming SA, Flunkert S, Kvistgaard AS et al. · 2025 · PloS one · PMID 41406156Open on PubMed
  4. Overall Evidence for Milk-Derived Proteins and Peptides in Blood after Digestion: A Systematic Review.Biondi Ryan MR, Zukaitis J, Sutantawong S et al. · 2025 · Nutrition reviews · PMID 40880247Open on PubMed
  5. Immunological effects of alpha-lactalbumin-enriched low-protein infant formula: A randomized controlled trial.Nilsson UT, Hernell O, Lönnerdal B et al. · 2025 · Journal of pediatric gastroenterology and nutrition · PMID 40910342Open on PubMed
  6. Evening Alpha-Lactalbumin Supplementation Alters Sleep Architecture and Reduces Morning Reaction Time in an Athletically Trained Population With Sleep Difficulties.Barnard J, Roberts S, Lastella M et al. · 2025 · International journal of sport nutrition and exercise metabolism · PMID 39832504Open on PubMed
  7. Impact of formula protein quantity and source on infant metabolism: serum, urine, and fecal metabolomes of a randomized controlled study.He X, Tinghäll Nilsson U, Mishchuk DO et al. · 2025 · The American journal of clinical nutrition · PMID 39921093Open on PubMed
  8. Pre-Sleep Alpha-Lactalbumin Supplementation Does Not Improve the Habitual Sleep and Performance of Sportspeople with Sleep Difficulties.Barnard J, Roberts S, Lastella M et al. · 2025 · Nutrients · PMID 40218954Open on PubMed
  9. Effect of 40:1 myo-inositol/D-chiro-inositol treatment on serum asprosin levels in polycystic ovary syndrome: a prospective randomized pilot study.Ozay OE, Ozay Y, Edebal O et al. · 2025 · Ginekologia polska · PMID 40665752Open on PubMed
  10. Alpha-lactalbumin and sleep: A systematic review.Barnard J, Roberts S, Kelly M et al. · 2024 · Journal of sleep research · PMID 38185736Open on PubMed
  11. Peptides Evaluated In Silico, In Vitro, and In Vivo as Therapeutic Tools for Obesity: A Systematic Review.Aguiar AJFC, de Medeiros WF, da Silva-Maia JK et al. · 2024 · International journal of molecular sciences · PMID 39273592Open on PubMed
  12. Low-Protein Infant Formula Enriched with Alpha-Lactalbumin during Early Infancy May Reduce Insulin Resistance at 12 Months: A Follow-Up of a Randomized Controlled Trial.Tinghäll Nilsson U, Lönnerdal B, Hernell O et al. · 2024 · Nutrients · PMID 38613059Open on PubMed

04 / EXPERT CONTEXT

Expert context—not evidence

Expert positions are dated context—not scientific evidence. They never raise the evidence status or become consensus by repetition.

No direct, source-verified endorsement is currently recorded. Research authorship or discussion alone is not treated as endorsement.

Educational information only—not medical advice. Product quality, dose, medicines, pregnancy, and kidney or liver disease can materially change safety.