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Supplement evidence

131 / 575Cardiometabolic

Cinnamon extract

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The short answer

Trials show inconsistent, usually modest glucose and lipid changes; species and preparation matter.

Evidence and scope
Mixed evidence

This status does not grade the ingredient for every goal, outcome, or person.

Important limitation
Trials are inconsistent or small, so a reliable clinically important benefit is not established.
Before deciding
Key concern: Cassia coumarin can injure liver; review diabetes drugs, anticoagulants, pregnancy, and allergy.

01 / PRACTICAL GUIDE

Dose, absorption, and combinations

These are indication-specific reference or studied ranges—not a personalized prescription. Start with the objective, then check the form, label, medicines, and health conditions.

Reference range by objective
Glucose-related research1–2 g/day powder-equivalent or standardized extract in trials

Reference or studied range—not a personalized prescription. The product label or a clinician may specify a different dose.

Dose source

More is not automatically better. A clinician or product label may specify a different amount.

Absorption / solubilityFormulation-dependent

Not usefully classified as a fat- or water-soluble vitamin; absorption depends on the salt, extract, delivery system, and meal.

How it is commonly taken

Take with meals and identify Ceylon versus cassia.

Do not combine casually

Cassia coumarin can injure liver; review diabetes drugs, anticoagulants, pregnancy, and allergy.

Dose and use source

Dose and use links lead to primary or official source material. Search links are discovery tools, not proof that every returned paper applies.

02 / EVIDENCE

What the research says

We keep supportive, mixed, negative, safety, and contextual findings together. The headline never replaces the underlying papers.

1research papers in this ledger
28unique primary studies represented
3,054unique participants represented

These are audited counts for this JIVANA collection, not search-result totals. Participants are counted once when multiple papers use the same cohort; review papers are not added again to participant totals.

Open the research timelineResearch timeline

Entries are ordered by publication year. A study period appears only when the source reports it.

2025
Mixed or qualifiedPMID 38917435 · CRD42022370332

Cinnamon supplementation and metabolic markers in type 2 diabetes

Pooled glucose and some lipid markers improved, including HbA1c by about 0.56 percentage points, but heterogeneity was very high for most estimates (often 88%–100%). Short trials, varied species and preparations, and surrogate outcomes prevent treating cinnamon as a replacement for diabetes care.

Study design and methods
Design
Systematic review and random-effects meta-analysis of 28 randomized controlled trials
Population
3,054 adults and older adults with type 2 diabetes
Intervention
Cinnamon supplements, including capsules and varied doses, versus placebo or control
Outcome
Fasting and postprandial glucose, HbA1c, insulin resistance, lipids, and body mass index
Open research record
Unscreened discovery appendix—not evidence51 candidate publicationsSearch run: Aug 21, 2026

Complete for the displayed PubMed query at the search timestamp—not for all databases or every possible synonym. Candidates can be irrelevant, duplicate the same study, or report negative findings. They are never summed as evidence or participants until screened.

03 / SOURCES

Start with the source material

The live search is for discovery only. Search-result counts change and are not included in the audited totals above.

Recent PubMed discovery recordsDirect links to the first 12 records returned by the reproducible search. These are discovery candidates—not reviewed summaries or a count of supportive findings.
  1. Efficacy and Safety of Cinnamomum zeylanicum (Ceylon cinnamon) for diabetes mellitus: a randomized, double blind, placebo-controlled clinical trial.Ranasinghe P, Galappatthy P, Constantine GR et al. · 2025 · Diabetes & metabolic syndrome · PMID 41412108Open on PubMed
  2. Olfactory training improves cognition and modifies brain networks in type 2 diabetes patients with mild cognitive impairment: A 16-week randomised controlled trial.Chao Y, Tong X, Zhang B et al. · 2025 · Diabetes, obesity & metabolism · PMID 40908892Open on PubMed
  3. Efficacy of cinnamon in reducing anthropometric measurements in individuals with type 2 diabetes: a clinical trial.Lira Neto JCG, Araújo MFM, Penha JCD et al. · 2025 · Revista brasileira de enfermagem · PMID 40667904Open on PubMed
  4. The efficacy and safety of berberine in combination with cinnamon supplementation in patients with type 2 diabetes: a randomized clinical trial.Mansour A, Sajjadi-Jazi SM, Gerami H et al. · 2025 · European journal of nutrition · PMID 39998703Open on PubMed
  5. Effects of cinnamon supplementation on metabolic biomarkers in individuals with type 2 diabetes: a systematic review and meta-analysis.de Moura SL, Gomes BGR, Guilarducci MJ et al. · 2025 · Nutrition reviews · PMID 38917435Open on PubMed
  6. Effects of Cinnamomum zeylanicum (Ceylon cinnamon) extract on lipid profile, glucose levels and its safety in adults: A randomized, double-blind, controlled trial.Muthukuda D, de Silva CK, Ajanthan S et al. · 2025 · PloS one · PMID 39854533Open on PubMed
  7. Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial.Moreira FD, Reis CEG, Gallassi AD et al. · 2024 · PloS one · PMID 39383145Open on PubMed
  8. Effect of cinnamon spice on continuously monitored glycemic response in adults with prediabetes: a 4-week randomized controlled crossover trial.Zelicha H, Yang J, Henning SM et al. · 2024 · The American journal of clinical nutrition · PMID 38290699Open on PubMed
  9. Effectiveness of a Food Supplement Based on Glucomannan, D-Chiro-Inositol, Cinnamomum zeylanicum Blume and Inulin in Patients with Metabolic Syndrome.Citarrella R, Chianetta R, Amodeo S et al. · 2024 · Nutrients · PMID 38257142Open on PubMed
  10. The effect of cinnamon supplementation on glycemic control in patients with type 2 diabetes mellitus: An updated systematic review and dose-response meta-analysis of randomized controlled trials.Moridpour AH, Kavyani Z, Khosravi S et al. · 2024 · Phytotherapy research : PTR · PMID 37818728Open on PubMed
  11. Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial.Lira Neto JCG, Araújo MFM, Araújo AVEC et al. · 2023 · Revista gaucha de enfermagem · PMID 37909519Open on PubMed
  12. The effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials.Sarmadi B, Musazadeh V, Dehghan P et al. · 2023 · Nutrition, metabolism, and cardiovascular diseases : NMCD · PMID 37500345Open on PubMed

04 / EXPERT CONTEXT

Expert context—not evidence

Expert positions are dated context—not scientific evidence. They never raise the evidence status or become consensus by repetition.

No direct, source-verified endorsement is currently recorded. Research authorship or discussion alone is not treated as endorsement.

Educational information only—not medical advice. Product quality, dose, medicines, pregnancy, and kidney or liver disease can materially change safety.