Supplement evidence

045 / 575Amino-acid-like compound

Taurine

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The short answer

Small human trials examine blood pressure, exercise, and metabolic outcomes.

Evidence and scope: Emerging evidence
This status does not grade the ingredient for every goal, outcome, or person.
Important limitation: Animal aging findings and biomarkers do not demonstrate human lifespan extension.
Before deciding: Long-term high-dose evidence and interactions remain insufficient.

01 / PRACTICAL GUIDE

Dose, absorption, and combinations

These are indication-specific reference or studied ranges—not a personalized prescription. Start with the objective, then check the form, label, medicines, and health conditions.

Reference range by objective

Blood pressure1–3 g/day in many short human trials

Reference or studied range—not a personalized prescription. The product label or a clinician may specify a different dose.

Dose source ↗

More is not automatically better. A clinician or product label may specify a different amount.

Absorption / solubilityWater-soluble

Water-soluble or readily water-dispersible. This does not mean excess is always harmless.

How it is commonly taken

May be divided with meals.

Do not combine casually

Blood-pressure medicines, bipolar disorder, kidney disease, and energy-drink stimulant mixtures warrant caution.

Dose and use source ↗

Dose and use links lead to primary or official source material. Search links are discovery tools, not proof that every returned paper applies.

02 / EVIDENCE

What the research says

We keep supportive, mixed, negative, safety, and contextual findings together. The headline never replaces the underlying papers.

4research papers in this ledger

44unique primary studies represented

—unique participants represented

These are audited counts for this JIVANA collection, not search-result totals. Participants are counted once when multiple papers use the same cohort; review papers are not added again to participant totals.

Open the research timelineResearch timeline

Entries are ordered by publication year. A study period appears only when the source reports it.

2025

Mixed or qualifiedPMID 41275513

Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors

Taurine modestly improved multiple cardiometabolic biomarkers, including HbA1c, lipids, and blood pressure. These short-term surrogate changes do not establish fewer cardiovascular events, diabetes complications, or longer life.

Published: 202534 primary studies represented

Study design and methods

Design: Systematic review and meta-analysis of 34 randomized trials
Population: Adults across varied cardiometabolic-risk populations
Intervention: Oral taurine supplements versus control
Outcome: Glucose control, lipids, blood pressure, liver enzymes, inflammation, and oxidative-stress biomarkers

Open research record ↗

2022

Does not support the tested claimPMID 35855073

Effect of taurine administration on dilated cardiomyopathy and heart failure in humans

Only one study was rated high quality, and pooled ejection fraction and stroke volume were not significantly improved. A formal outcome trial is still needed.

Published: 202211 primary studies represented

Study design and methods

Design: Systematic review of 11 human studies
Population: People with all-cause heart failure; no study specifically enrolled dilated cardiomyopathy
Intervention: Taurine 500 mg–6 g/day for 2–48 weeks
Outcome: Symptoms, cardiac function, exercise capacity, and hemodynamics

Funding or conflict note: Possible overlap with cardiometabolic trials prevents separate aggregate counting.

Open research record ↗

2018

Mixed or qualifiedPMID 29546641

The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance

Pooled endurance performance showed a small-to-moderate benefit, without a clear dose or acute-versus-chronic pattern. Small heterogeneous tasks do not establish a universal athletic-performance effect.

Published: 2018Duration: Single dose to 2 weeks10 primary studies represented

Study design and methods

Design: Meta-analysis of 10 peer-reviewed trials
Population: Participants completing varied endurance tasks
Intervention: Isolated oral taurine 1–6 g/day versus control
Outcome: Overall endurance and time-to-exhaustion performance

Open research record ↗

2016

Supports a specific usePMID 26781281

Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension

Clinic and ambulatory blood pressure and vasodilation favored taurine, especially in high-normal baseline pressure. This single short trial did not test cardiovascular events.

Published: 2016Duration: 12 weeksn=120 participants

Study design and methods

Design: Randomized, double-blind, placebo-controlled trial
Population: 120 adults with prehypertension
Intervention: Taurine 1.6 g/day or placebo
Outcome: Clinic and ambulatory blood pressure and vascular function

Funding or conflict note: This trial is represented in the broader 2025 synthesis and is excluded from aggregate totals.

Open research record ↗

Unscreened discovery appendix—not evidence403 candidate publicationsSearch run: Aug 21, 2026

Complete for the displayed PubMed query at the search timestamp—not for all databases or every possible synonym. Candidates can be irrelevant, duplicate the same study, or report negative findings. They are never summed as evidence or participants until screened.

03 / SOURCES

Start with the source material

Official evidence overviewPubMed human-evidence index Live PubMed discovery searchNational Library of Medicine

The live search is for discovery only. Search-result counts change and are not included in the audited totals above.

Recent PubMed discovery recordsDirect links to the first 12 records returned by the reproducible search. These are discovery candidates—not reviewed summaries or a count of supportive findings.

04 / EXPERT CONTEXT

Expert context—not evidence

Expert positions are dated context—not scientific evidence. They never raise the evidence status or become consensus by repetition.

No direct, source-verified endorsement is currently recorded. Research authorship or discussion alone is not treated as endorsement.